The COVID-19 pandemic has enormously altered people’s life. Every day is a new challenge with the evolving coronavirus coming up with different mutations. The second wave showed a massive outbreak in India, with the delta variant emerging as the most infectious one. Since then, there have been many questions in everyone’s mind about this deadly virus. When will the pandemic end? Why does the coronavirus change? Will people be sick with the new variants? Will the vaccine work on the new variants? Through this article let us try and understand the coronavirus in detail and the role of vaccines in fighting this pandemic.